A serious new hurdle for CRISPR: Edited cells might cause cancer, two studies find Print
Written by Sharon Begley | STAT   
Tuesday, 12 June 2018 17:54
 
Editing cells' genomes with CRISPR-Cas9 might increase the risk that the altered cells, intended to treat disease, will trigger cancer, two studies published on Monday <6.11.18> warn - a potential game-changer for the companies developing CRISPR-based therapies. In the studies, published in Nature Medicine, scientists found that cells whose genomes are successfully edited by CRISPR-Cas9 have the potential to seed tumors inside a patient. That could make some CRISPR'd cells ticking time bombs, according to researchers from Sweden's Karolinska Institute and, separately, Novartis.
 
Last Updated on Tuesday, 12 June 2018 17:57