Focus

What if a virus could reverse antibiotic resistance?

In promising experiments, phage therapy forces bacteria into a no-win dilemma that lowers their defenses against drugs they’d evolved to withstand Peering through his microscope in 1910, Franco-Canadian microbiologist Félix d'Hérelle noticed some “clear spots” in his bacterial cultures, an anomaly that turned out to be viruses preying on the bacteria. Years later, d'Hérelle would come to use...

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Needing Mental Health Care, He Got Trapped in His Insurer’s Ghost Network

ProPublica is a Pulitzer Prize-winning investigative newsroom. Sign up for The Big Story newsletter to receive stories like this one in your inbox. This story was originally published by ProPublica. Series: America’s Mental Barrier - How Insurers Interfere With Mental Health Care Early one morning in February 2023, before the sun rose over Phoenix, Ravi Coutinho went on a walk and, for a brief...

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Mitochondria keep your brain cells alive − helping them run smoothly may protect against Parkinson’s disease

Mitochondria actively divide, multiply and move around in your cells. Nanoclustering/Science Photo Library via Getty Images ~~~~~ In 1817, a British physician named James Parkinson published An Essay on the Shaking Palsy, describing for the first time cases of a neurodegenerative disorder now known as Parkinson’s disease. Today, Parkinson’s disease is the second most common neurodegenerative...

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The public deserves honesty and respect. Scientists need to do a better job delivering, says Frederic Bertley, president of the COSI Science Center.

Frederic Bertley is an immunologist and educator who has helped develop DNA vaccines for HIV/AIDS and has worked on global health projects in Haiti, Sudan, and the Canadian Arctic. Since 2017, he has been president and CEO of the Center of Science and Industry (COSI), a 320,000-square-foot science museum and research hub in Columbus, Ohio. He also co-created and hosts the television show QED...

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Does New Study on Masks Show That They Work?

Whether to wear a face mask to prevent respiratory illnesses has been one of the most divisive debates during the pandemic. After a Cochrane review in 2023 found that face masks made “little or no difference” to the spread of respiratory viruses, the issue became highly politicized. Tom Jefferson, lead author of the Cochrane review, told me “There is just no evidence that they make any...

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To pee or not to pee? That is a question for the bladder — and the brain

How do we sense the need to urinate? The basic urge is surprisingly complex and can go awry as we age. You’re driving somewhere, eyes on the road, when you start to feel a tingling sensation in your lower abdomen. That extra-large Coke you drank an hour ago has made its way through your kidneys into your bladder. “Time to pull over,” you think, scanning for an exit ramp. To most people, pulling...

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